Yes, I am having the same problem. I have only been using Esquilo for about a month, and am generally not able to access my device with the Nest (i.e., remotely through the cloud). Even when I reset (power off - power on) the Esquilo, and the Nest page shows my Esquilo to be online, most of the time I cannot actually access it -- eventually get the 403 Forbidden message. All this, while the Esquilo is operating and working fine over my local network.
I started a new topic on my issue because I did not see any actual solution to the problem identified for this one.
Using a MacBook Pro with OSX 10.12.4 (Sierra).